Active ingredient: Methylphenidate - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C14H19NO2

Chemical Name

methyl 2-phenyl-2-(2-piperidyl)acetate

Chemical Structure

Molecular Weight

233.306 g/mol

Physical State

Solid

Melting Point

224-226oC

Water Solubility

1255mg/L

Isoelectric Point

8.77

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not applicable

Primary Drug Target

Name	Sodium-dependent dopamine re-uptake pump
Gene Name	SLC6A3
Synonyms	Sodium-dependent dopamine transporter; DA transporter; DAT
General Function	General function prediction only
Specific Function	Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals