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Active ingredient: Methacycline - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula


Chemical Name

2-(amino-hydroxy-methylidene)-4-dimethylamino-5,10,11,12a-tetrahydroxy-6- methylidene-4a,5,5a,12a-tetrahydro-4H-tetracene-1,3,12-trione

Chemical Structure

Molecular Weight

442.419 g/mol

Physical State


Melting Point

Not Available

Water Solubility

Not Available

Isoelectric Point

Not Available

Organisms Affected

Enteric bacteria and other eubacteria

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
Name50S subunit of the 70S ribosome of bacteria
Gene NamerplJ
Synonyms50S ribosomal protein L10
General FunctionTranslation, ribosomal structure and biogenesis
Specific FunctionProtein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA

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