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Active ingredient: Mercaptopurine - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C5H4N4S

Chemical Name

7H-purine-6-thiol

Chemical Structure

Molecular Weight

152.178 g/mol

Physical State

Solid

Melting Point

313 oC

Water Solubility

6.85 mg/mL

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Xanthine dehydrogenase/oxidase

Primary Drug Target
NamePurine nucleoside phosphorylase
Gene NameNP
SynonymsPurine nucleoside phosphorylase; EC 2.4.2.1; Inosine phosphorylase; PNP
General FunctionNucleotide transport and metabolism
Pathwaymap00230 Purine metabolism map00240 Pyrimidine metabolism map00760 Nicotinate and nicotinamide metabolism
Reactionpurine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate

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