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Active ingredient: Mecamylamine - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C11H21N

Chemical Name

N,2,3,3-tetramethylnorbornan-2-amine

Chemical Structure

Molecular Weight

167.291 g/mol

Physical State

Liquid

Melting Point

<25 oC

Water Solubility

Not Available

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameNicotinic acetylcholine Receptor alpha2/alpha3
Gene NameCHRNA2
SynonymsNeuronal acetylcholine receptor protein, alpha-2 subunit precursor
Specific FunctionAfter binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane

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