Chemisty and Biological Activity
Chemical Formula
C15H10Cl2N2O2
Chemical Name
9-chloro-6-(2-chlorophenyl)-4-hydroxy-2,5-diazabicyclo[5.4.0]undeca- 5,8,10,12-tetraen-3-one
Chemical Structure
Molecular Weight
321.158 g/mol
Physical State
Solid
Melting Point
166-168oC
Water Solubility
0.08 mg/mL
Isoelectric Point
13
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
UDP-glucuronic acid
Primary Drug Target
| Name | Benzodiazepine Receptor | | Gene Name | BZRP | | Synonyms | Peripheral-type benzodiazepine receptor; PBR; PKBS; Mitochondrial benzodiazepine receptor | | General Function | Signal transduction mechanisms | | Specific Function | Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme |
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