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Active ingredient: Liothyronine - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula


Chemical Name

2-amino-3-[4-(4-hydroxy-3-iodo-phenoxy)-3,5-diiodo-phenyl]-propanoic acid

Chemical Structure

Molecular Weight

650.974 g/mol

Physical State


Melting Point

236.5 oC

Water Solubility

3.96 mg/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameThyroid hormone receptor beta-1
Gene NameTHRB
Specific FunctionHigh affinity receptor for triiodothyronine

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