Brands, Medical Use, Clinical Data
Drug Category
- Anti-Estrogen Agents
- Antineoplastic Agents
Dosage Forms
- Subcutaneous implant
- Solution (subcutaneous injection)
- Solution (IM injection)
Brands / Synonyms
Eligard; Eligard (Atrix Labs/QLT Inc)
; Lupron; Lupron Depot; Lupron Depot - PED; Lupron Depot PED; Viadur
Description
Synthetic 9 residue peptide analog of gonadotropin releasing hormone.
Indications
For treatment of prostate cancer, endometriosis, uterine fibroids and premature puberty
Pharmacology
Used in the palliative treatment of advanced prostate cancer. Leuprolide is a luteinizing hormone agonist that results in suppression of testicular or follicular steroidogenesis.
Mechanism of Action
Leuprolide binds to the gonadotropin releasing hormone receptor and acts as a potent inhibitor of gonadotropin secretion.
Absorption
Not Available
Toxicity
Not Available
Biotrnasformation / Drug Metabolism
Not Available
Contraindications
Not Available
Drug Interactions
Not Available
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