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Active ingredient: Leuprolide - Brands, Medical Use, Clinical Data

Brands, Medical Use, Clinical Data

Drug Category

  • Anti-Estrogen Agents
  • Antineoplastic Agents

Dosage Forms

  • Subcutaneous implant
  • Solution (subcutaneous injection)
  • Solution (IM injection)

Brands / Synonyms

Eligard; Eligard (Atrix Labs/QLT Inc) ; Lupron; Lupron Depot; Lupron Depot - PED; Lupron Depot PED; Viadur

Description

Synthetic 9 residue peptide analog of gonadotropin releasing hormone.

Indications

For treatment of prostate cancer, endometriosis, uterine fibroids and premature puberty

Pharmacology

Used in the palliative treatment of advanced prostate cancer. Leuprolide is a luteinizing hormone agonist that results in suppression of testicular or follicular steroidogenesis.

Mechanism of Action

Leuprolide binds to the gonadotropin releasing hormone receptor and acts as a potent inhibitor of gonadotropin secretion.

Absorption

Not Available

Toxicity

Not Available

Biotrnasformation / Drug Metabolism

Not Available

Contraindications

Not Available

Drug Interactions

Not Available

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