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Active ingredient: Isosorbide Dinitrate - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula


Chemical Name


Chemical Structure

Molecular Weight

236.136 g/mol

Physical State


Melting Point

70 oC

Water Solubility

1.089 mg/mL

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)


Primary Drug Target
NameAtrial natriuretic peptide receptor A
Gene NameNPR1
SynonymsAtrial natriuretic peptide receptor A precursor; ANP-A; ANPRA; GC-A; Guanylate cyclase; EC; NPR-A; Atrial natriuretic peptide A-type receptor
General FunctionSignal transduction mechanisms
Specific FunctionReceptor for atrial natriuretic peptide. Has guanylate cyclase activity on binding of ANF
Pathwaymap00230 Purine metabolism
ReactionGTP = 3',5'-cyclic GMP + diphosphate

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