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Active ingredient: Imiquimod - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C14H16N4

Chemical Name

Not Available

Chemical Structure

Molecular Weight

240.304 g/mol

Physical State

Solid

Melting Point

292-294 oC

Water Solubility

Poorly soluble

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameToll-like receptor 7 precursor
Gene NameTLR7
Specific FunctionParticipates in the innate immune response to microbial agents. Acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response

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