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Active ingredient: Imipramine - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula


Chemical Name

Not Available

Chemical Structure

Molecular Weight

280.407 g/mol

Physical State


Melting Point

174.5 oC

Water Solubility

18.2 mg/L

Isoelectric Point


Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)


Primary Drug Target
NameSodium-dependent noradrenaline transporter
Gene NameSLC6A2
SynonymsNorepinephrine transporter; NET
General FunctionGeneral function prediction only
Specific FunctionAmine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals

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