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Active ingredient: Hydromorphone - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C17H19NO3

Chemical Name

4,5 alpha-epoxy-3-hydroxy-17-methyl morphinan-6-one

Chemical Structure

Molecular Weight

285.338 g/mol

Physical State

Solid

Melting Point

266-267 oC

Water Solubility

Not Available

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP3A4; CYP2C9

Primary Drug Target
NameOpioid mu Receptor (OP1)
Gene NameOPRM1
SynonymsMu-type opioid receptor; MOR-1
Specific FunctionInhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin

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