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Active ingredient: Haloperidol - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C21H23ClFNO2

Chemical Name

4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1- one

Chemical Structure

Molecular Weight

375.864 g/mol

Physical State

Solid

Melting Point

151.5 oC

Water Solubility

14 mg/L

Isoelectric Point

8.66

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP1A2; CYP2D6

Primary Drug Target
NameD(2) Dopamine Receptor
Gene NameDRD2
SynonymsD(2 dopamine receptor; Dopamine D2 receptor
General FunctionReceptor activity and cell communication
Specific FunctionThis is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase

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