Chemisty and Biological Activity
Chemical Formula
Not Available
Chemical Name
N-acetyl-3-(2-napthyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D- alanyl-L-seryl-L-tyrosyl-N 9 ,N 10 -diethyl- D-homoarginyl-L-leucyl- N 9 ,N 10 -diethyl-L-homoarginyl-L-prolyl-D-alanylamide acetate
Chemical Structure
img=Ganirelix_APRD00995_ZOOM.gif
Molecular Weight
1570.4 g/mol
Physical State
Liquid
Melting Point
Not Available
Water Solubility
Not Available
Isoelectric Point
Not Available
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
| Name | Gonadotropin-releasing hormone receptor | | Gene Name | GNRHR | | Synonyms | GnRH receptor; GnRH-R | | Specific Function | Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Isoform 2 may act a an inhibitor of GnRH-R signaling |
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