Active ingredient: Flutamide - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C11H11F3N2O3

Chemical Name

2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-propanamide

Chemical Structure

Molecular Weight

276.212 g/mol

Physical State

Solid

Melting Point

111-113 oC

Water Solubility

9.45 mg/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP1A2

Primary Drug Target

Name	Androgen receptor
Gene Name	AR
Synonyms	Androgen receptor; Dihydrotestosterone receptor
General Function	General function prediction only
Specific Function	The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Activated, but not phosphorylated, by HIPK3