Active ingredient: Flumazenil - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C15H14FN3O3

Chemical Name

Not Available

Chemical Structure

Molecular Weight

303.288 g/mol

Physical State

Solid

Melting Point

201-203 oC

Water Solubility

128 mg/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target

Name	GABA-A Receptor
Gene Name	GABRA1
Synonyms	Gamma-aminobutyric-acid receptor alpha-1 subunit precursor; GABA(A) receptor
Specific Function	GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel