DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Active ingredient: Etodolac - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C17H21NO3

Chemical Name

1,8-diethyl-1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acid

Chemical Structure

Molecular Weight

287.354 g/mol

Physical State

Solid

Melting Point

145-148 oC

Water Solubility

16 mg/L

Isoelectric Point

4.65

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP2C9

Primary Drug Target
NameCOX-1
Gene NamePTGS1
SynonymsProstaglandin G/H synthase 1 precursor; EC 1.14.99.1; Cyclooxygenase-1; COX-1; Prostaglandin-endoperoxide synthase 1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1
Specific FunctionMay play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells
Pathwaymap00590 Prostaglandin and leukotriene metabolism
Reactionarachidonate + AH2 + 2 O2 = prostaglandin H2 + A + H2O

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017