Chemisty and Biological Activity
Chemical Formula
C17H19N3O3S
Chemical Name
5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H- benzoimidazole
Chemical Structure
Molecular Weight
345.417 g/mol
Physical State
Solid
Melting Point
155 oC
Water Solubility
Very slightly soluble in water
Isoelectric Point
Not Available
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
CYP2C19; CYP3A4
Primary Drug Target
| Name | H+/K+ -ATPase | | Gene Name | ATP4A | | Synonyms | Potassium-transporting ATPase alpha chain 1; EC 3.6.3.10; Proton pump; Gastric H+/K+ ATPase alpha subunit | | General Function | Inorganic ion transport and metabolism | | Specific Function | Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | | Pathway | map00190 Oxidative phosphorylation | | Reaction | ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in) |
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