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Active ingredient: Epirubicin - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C27H29NO11

Chemical Name

10-(4-amino-5-hydroxy-6-methyl-oxan-2-yl)oxy-6,8,11-trihydroxy-8-(2- hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione

Chemical Structure

Molecular Weight

543.519 g/mol

Physical State

Solid

Melting Point

344.53oC

Water Solubility

0.093 mg/ml

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP3A4

Primary Drug Target
NameDNA Helicase
Gene NameCHD1
SynonymsChromodomain-helicase-DNA-binding protein 1; CHD-1
General FunctionTranscription
Specific FunctionSequence-selective DNA-binding protein. Could play an important role in gene regulation

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