Chemisty and Biological Activity
Chemical Formula
C17H22N2O
Chemical Name
N,N-dimethyl-2-(1-phenyl-1-pyridin-2-yl-ethoxy)-ethanamine
Chemical Structure
Molecular Weight
270.369 g/mol
Physical State
Liquid
Melting Point
< 25 oC
Water Solubility
1 g/ml (succinate salt)
Isoelectric Point
5.8 and 9.3
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
| Name | Histamine H1 receptor | | Gene Name | HRH1 | | Specific Function | In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system |
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