Chemisty and Biological Activity
Chemical Formula
C16H13ClN2O
Chemical Name
9-chloro-2-methyl-6-phenyl-2,5-diazabicyclo[5.4.0]undeca-5,8,10,12-tetraen- 3-one
Chemical Structure
Molecular Weight
284.74 g/mol
Physical State
solid
Melting Point
125-126oC
Water Solubility
Slightly soluble (50 mg/L)
Isoelectric Point
3.4
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
CYP3A4; CYP1A2
Primary Drug Target
| Name | Benzodiazepine Receptor | | Gene Name | BZRP | | Synonyms | Peripheral-type benzodiazepine receptor; PBR; PKBS; Mitochondrial benzodiazepine receptor | | General Function | Signal transduction mechanisms | | Specific Function | Responsible for the manifestation of peripheral-type benzodiazepine recognition sites and is most likely to comprise binding domains for benzodiazepines and isoquinoline carboxamides. May play a role in the transport of porphyrins and heme |
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