Brands, Medical Use, Clinical Data
Drug Category
Dosage Forms
Brands / Synonyms
Acide amidotrizoique; Acidum amidotrizoicum; Acidum diacetylaminotrijodbenzoicum; Amidotrizoate; AmiDOTrizoic acid; Angiovist 282; Cardiografin; Conray 35; Diat; DIAT [German]; Diatriazoate; Diatrizoate sodium; Diatrizoate sodium salt; Diatrizoesaeure; Diatrizoesaure; Diatrizoesaure [German]; Diatrizoic acid; Diatrizoic acid sodium salt; Diatrizoic acid [USAN:BAN]; Gastrografin; Hypaque; Hypaque 50; Hypaque sodium; Iothalamate; Meglumine diatrizoate; Methalamic acid; Odiston; Reno-60; Reno-dip; Renografin 76; Sodium amidotrizoate; Sodium diatrizoate; Triombrin; Triombrin [Russian]; Triombrine; Urografic acid, sodium salt; Urografin acid; Urogranoic acid; Urotrast; Urovison; Urovist Cysto; Urovist Cysto Pediatric; Urovist Meglumine Diu/ct; Urovist Sodium 300; Vascoray
Indications
Used, alone or in combination, for a wide variety of diagnostic imaging methods, including angiography, urography, cholangiography, computed tomography, hysterosalpingography, and retrograde pyelography.
Pharmacology
Diatrizoate is the most commonly used water-soluble, iodinated, radiopaque x-ray contrast medium. Radiopaque agents are drugs used to help diagnose certain medical problems. They contain iodine, which blocks x-rays. Depending on how the radiopaque agent is given, it localizes or builds up in certain areas of the body. The resulting high level of iodine allows the x-rays to make a "picture" of the area. The areas of the body in which the radiopaque agent localizes will appear white on the x-ray film. This creates the needed distinction, or contrast, between one organ and other tissues. The contrast will help the doctor see any special conditions that may exist in that organ or part of the body.
Mechanism of Action
Not Available
Absorption
Not Available
Toxicity
Not Available
Biotrnasformation / Drug Metabolism
Not Available
Contraindications
Not Available
Drug Interactions
May interact with thyroid medication (e.g., levothyroxine), iodine-containing products, antacids, H2-antagonists (e.g., famotidine, ranitidine), and proton pump inhibitors (e.g., lansoprazole, omeprazole). This product can affect the results of certain lab tests.
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