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Active ingredient: Desmopressin - Brands, Medical Use, Clinical Data

Brands, Medical Use, Clinical Data

Drug Category

  • Renal Agents

Dosage Forms

  • Tablet

Brands / Synonyms

1-Deamino-8-D-arginine vasopressin; 1-Desamino-8-D-arginine vasopressin; 1-Desamino-8-d-arginine-vasopressin; Concentraid; Ddavp; Ddavp Injection; Ddavp Nasal; Desamino-8-D-arginine vasopressin, l-; Desmopresina [INN-Spanish]; Desmopressin; Desmopressine [INN-French]; Desmopressinum [INN-Latin]; Stimate

Description

Desmopressin is a chemical that is similar to a hormone found naturally in your body. It increases urine concentration and decreases urine production. Desmopressin is used to prevent and control excessive thirst, urination, and dehydration caused by injury, surgery, and certain medical conditions, allowing you to sleep through the night without awakening to urinate. It is also used to treat specific types of diabetes insipidus and conditions after head injury or pituitary surgery.

Indications

For the management of primary nocturnal enuresis and indicated as antidiuretic replacement therapy in the management of central diabetes insipidus and for the management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary

Pharmacology

Desmopressin is a synthetic analogue of the natural pituitary hormone 8-arginine vasopressin (ADH), an antidiuretic hormone affecting renal water conservation. Desmopressin is indicated as antidiuretic replacement therapy in the management of central diabetes insipidus and for the management of the temporary polyuria and polydipsia following head trauma or surgery in the pituitary region and is also indicated for the management of primary nocturnal enuresis.

Mechanism of Action

Desmopressin emulates the actions of the natural pituitary hormone 8-arginine vasopressin (ADH).

Absorption

Not Available

Toxicity

Not Available

Biotrnasformation / Drug Metabolism

Not Available

Contraindications

Not Available

Drug Interactions

Not Available

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