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Active ingredient: Daunorubicin - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C27H29NO10

Chemical Name

8-acetyl-10-(4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl)oxy-6,8,11- trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione

Chemical Structure

Molecular Weight

527.52 g/mol

Physical State

Solid

Melting Point

208-209 oC

Water Solubility

39.2 mg/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameDNA
Gene NameNot Applicable
SynonymsDeoxyribonucleic acid
General FunctionBiological information storage and information transfer
Specific FunctionDNA is the molecule of heredity, as it is responsible for the genetic propagation of most inherited traits. It is a polynucleic acid that carries genetic information on cell growth, division, and function. DNA consists of two long strands of nucleotides twisted into a double helix and held together by hydrogen bonds. The sequence of nucleotides determines hereditary characteristics. Each strand serves as the template for subsequent DNA replication and as a template for mRNA production, leading to protein synthesis via ribosomes.
PathwayMap03030 DNA replication Map03020 RNA transcription
ReactionDNA + DNA polymerase + nNTP = 2 DNA + nNDP DNA + RNA polymerase + NTP = mRNA + nNDP

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