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Active ingredient: Clozapine - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula


Chemical Name

Not Available

Chemical Structure

Molecular Weight

326.823 g/mol

Physical State


Melting Point

183-184 oC

Water Solubility

11.8 mg/L

Isoelectric Point


Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)


Primary Drug Target
NameD(4) Dopamine Receptor
Gene NameDRD4
SynonymsD(4) dopamine receptor; D(2C) dopamine receptor
General FunctionCell cycle control, cell division, chromosome partitioning
Specific FunctionThis is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase

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