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Active ingredient: Clopidogrel - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C16H16ClNO2S

Chemical Name

methyl (2S)-2-(2-chlorophenyl)-2-(9-thia-4-azabicyclo[4.3.0]nona-7,10-dien- 4-yl)acetate

Chemical Structure

Molecular Weight

321.822 g/mol

Physical State

solid

Melting Point

158oC

Water Solubility

50.78 mg/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP3A4

Primary Drug Target
NameP2Y12 platelet ADP Receptor
Gene NameP2RY12
SynonymsP2Y purinoceptor 12; P2Y12; P2Y12 platelet ADP receptor; P2Y(ADP); ADP-glucose receptor; ADPG-R; P2Y(AC); P2Y(cyc); P2T(AC); SP1999
Specific FunctionReceptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Involved in platelets aggregation

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