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Active ingredient: Cilostazol - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C20H27N5O2

Chemical Name

6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one

Chemical Structure

Molecular Weight

369.461 g/mol

Physical State

Solid

Melting Point

160 oC

Water Solubility

Not Available

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP2C19; CYP3A4

Primary Drug Target
NamecAMP Phosphodiesterase
Gene NamePDE4B
SynonymscAMP-specific 3',5'-cyclic phosphodiesterase 4B; EC 3.1.4.17; DPDE4; PDE32
Specific FunctionMay be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents
Pathwaymap00230 Purine metabolism
Reactionnucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate

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