Chemisty and Biological Activity
Chemical Formula
C12H17NO2
Chemical Name
6-cyclohexyl-1-hydroxy-4-methyl-pyridin-2-one
Chemical Structure
Molecular Weight
207.269 g/mol
Physical State
Solid
Melting Point
144 oC
Water Solubility
Not Available
Isoelectric Point
Not Available
Organisms Affected
Humans, other mammals, yeast and other fungi
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
| Name | Arachidonate 5-lipoxygenase | | Gene Name | ALOX15 | | Synonyms | Arachidonate 15-lipoxygenase; EC 1.13.11.33; Arachidonate omega-6 lipoxygenase; 15-LOX | | Specific Function | Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid | | Pathway | map00590 Prostaglandin and leukotriene metabolism | | Reaction | arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate |
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