Chemisty and Biological Activity
Chemical Formula
C66H103N17O16S
Chemical Name
4-[2-[[2-(1-amino-2-methyl-butyl)-4,5-dihydro-1,3-thiazol-5- yl]carbonylamino]-4-methyl-pentanoyl]amino-5-[1-[[18-(3-aminopropyl)-12- benzyl-15-butan-2-yl-3-(carbamoylmethyl)-6-(carboxymethyl)-9-(3H-imidazol- 4-ylmethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19- heptazacyclopentacos-21-yl]carbamoyl]-2-methyl-butyl]amino-5-oxo- pentanoic acid
Chemical Structure
Molecular Weight
1422.69 g/mol
Physical State
Solid
Melting Point
221 - 225 oC
Water Solubility
Freely soluble
Isoelectric Point
Not Available
Organisms Affected
Enteric bacteria and other eubacteria
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
| Name | Probable low molecular weight protein-tyrosine-phosphatase epsP | | Gene Name | epsP | | Synonyms | EC 3.1.3.48 | | General Function | Signal transduction mechanisms | | Specific Function | May be involved in assembly or function of the EPS I polymerization/export complex and/or the epsB ATPase. Alternatively it may function in the removal of the terminal phosphate from C55-isoprenyl pyrophosphate in order to recycle the C55-isoprenyl phosphate lipid carrier used in the synthesis of polysaccharide repeat units | | Reaction | protein tyrosine phosphate + H2O = protein tyrosine + phosphate |
|
