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Active ingredient: Azithromycin - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C38H72N2O12

Chemical Name

11-(4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl)oxy-2-ethyl-3,4,10- trihydroxy-13-(5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl)oxy- 3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one

Chemical Structure

Molecular Weight

748.985 g/mol

Physical State

Solid

Melting Point

113-115 oC

Water Solubility

slight

Isoelectric Point

8.74

Organisms Affected

Enteric bacteria and other eubacteria

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
Name50S subunit of the 70S ribosome of bacteria
Gene NamerplJ
Synonyms50S ribosomal protein L10
General FunctionTranslation, ribosomal structure and biogenesis
Specific FunctionProtein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA

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