Chemisty and Biological Activity
Chemical Formula
C38H72N2O12
Chemical Name
11-(4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl)oxy-2-ethyl-3,4,10- trihydroxy-13-(5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl)oxy- 3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one
Chemical Structure
Molecular Weight
748.985 g/mol
Physical State
Solid
Melting Point
113-115 oC
Water Solubility
slight
Isoelectric Point
8.74
Organisms Affected
Enteric bacteria and other eubacteria
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
Name | 50S subunit of the 70S ribosome of bacteria | Gene Name | rplJ | Synonyms | 50S ribosomal protein L10 | General Function | Translation, ribosomal structure and biogenesis | Specific Function | Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA |
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