Active ingredient: Atenolol - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C14H22N2O3

Chemical Name

2-[4-[2-hydroxy-3-(1-methylethylamino)propoxy]phenyl]ethanamide

Chemical Structure

Molecular Weight

266.336 g/mol

Physical State

Solid

Melting Point

146-148oC

Water Solubility

13.5 mg/mL

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP2D6

Primary Drug Target

Name	beta1-selective beta-adrenergic receptor
Gene Name	ADRB1
Synonyms	Beta-1 adrenergic receptor; Beta-1 adrenoceptor; Beta-1 adrenoreceptor
General Function	Receptor activity and cell communication
Specific Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximatively equal affinity