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Active ingredient: Ardeparin - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

(C26H40N2O36S5)n

Chemical Name

6-[5-acetylamino-4,6-dihydroxy-2-(sulfooxymethyl)tetrahydropyran-3-yl]oxy-3- [5-(6-carboxy-4,5-dihydroxy-3-sulfooxy-tetrahydropyran-2-yl)oxy-6- (hydroxymethyl)-3-sulfoamino-4-sulfooxy-tetrahydropyran-2-yl]oxy-4-hydroxy- 5-sulfooxy-tetrahydropyran-2-carboxylic acid

Chemical Structure

Molecular Weight

1134.93 g/mol

Physical State

Solid

Melting Point

Not Available

Water Solubility

Soluble

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameAntithrombin III (ATIII)
Gene NameSERPINC1
SynonymsAntithrombin-III precursor; ATIII
Specific FunctionMost important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin

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