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Active ingredient: Amiodarone - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula


Chemical Name

(2-butylbenzofuran-3-yl)-[4-(2-diethylaminoethoxy)-3,5-diiodo-phenyl]- methanone

Chemical Structure

Molecular Weight

645.312 g/mol

Physical State


Melting Point

Not Available

Water Solubility


Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)


Primary Drug Target
NameAlpha-1A Adrenergic Receptor
Gene NameADRA1A
SynonymsAlpha-1A adrenergic receptor; Alpha 1A-adrenoceptor; Alpha 1A- adrenoreceptor; Alpha-1C adrenergic receptor; Alpha adrenergic receptor 1c
General FunctionReceptor activity and cell communication
Specific FunctionThis alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins

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