Chemisty and Biological Activity
Chemical Formula
C7H7NO3
Chemical Name
4-amino-2-hydroxy-benzoic acid
Chemical Structure
Molecular Weight
153.135 g/mol
Physical State
Solid
Melting Point
150.5 oC
Water Solubility
1690 mg/L
Isoelectric Point
2.05
Organisms Affected
Mycobacteria
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
| Name | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | | Gene Name | folK | | Synonyms | EC 2.7.6.3; 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; HPPK; 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; PPPK | | General Function | Coenzyme transport and metabolism | | Pathway | map00790 Folate biosynthesis | | Reaction | ATP + 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine = AMP + 2-amino-7,8-dihydro-4-hydroxy-6-(diphosphooxymethyl)pteridine |
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