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Active ingredient: Aminophylline - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C16H24N10O4

Chemical Name

1,3-dimethyl-7H-purine-2,6-dione; ethane-1,2-diamine

Chemical Structure

Molecular Weight

420.427 g/mol

Physical State

Solid

Melting Point

Not Available

Water Solubility

2E+005 mg/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameType III phosphodiesterase
Gene NamePDE3A
SynonymscGMP-inhibited 3',5'-cyclic phosphodiesterase A; EC 3.1.4.17; Cyclic GMP inhibited phosphodiesterase A; CGI-PDE A
Specific FunctionHydrolyzes both cyclic AMP (cAMP) and cyclic GMP (cGMP)
Pathwaymap00230 Purine metabolism
Reactionnucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate

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