Chemisty and Biological Activity
Chemical Formula
C22H43N5O13
Chemical Name
4-amino-N-[5-amino-2-[4-amino-3,5-dihydroxy-6- (hydroxymethyl)tetrahydropyran-2-yl]oxy-4-[6-(aminomethyl)-3,4,5- trihydroxy-tetrahydropyran-2-yl]oxy-3-hydroxy-cyclohexyl]-2-hydroxy- butanamide
Chemical Structure
Molecular Weight
585.603 g/mol
Physical State
Solid
Melting Point
203-204 oC
Water Solubility
1.85E+005 mg/L
Isoelectric Point
Not Available
Organisms Affected
Enteric bacteria and other eubacteria
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
| Name | 30S ribosomal protein S12 | | Gene Name | rpsL | | Synonyms | 30S ribosomal protein S12 | | General Function | Translation, ribosomal structure and biogenesis | | Specific Function | Cryo-EM studies suggest that S12 contacts the EF-Tu bound tRNA in the A-site during codon-recognition. This contact is most likely broken as the aminoacyl-tRNA moves into the peptidyl transferase center in the 50S subunit |
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