Active ingredient: Alprenolol - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C15H23NO2

Chemical Name

1-(1-methylethylamino)-3-(2-prop-2-enylphenoxy)-propan-2-ol

Chemical Structure

Molecular Weight

249.349 g/mol

Physical State

Solid

Melting Point

107-109 oC

Water Solubility

547 mg/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP2D6

Primary Drug Target

Name	Beta-1 adrenergic receptor
Gene Name	ADRB1
Synonyms	Beta-1 adrenoceptor; Beta-1 adrenoreceptor
Specific Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximatively equal affinity.