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Active ingredient: Almotriptan - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C17H25N3O2S

Chemical Name

N,N-dimethyl-2-[5-(pyrrolidin-1-ylsulfonylmethyl)-1H-indol-3-yl]- ethanamine

Chemical Structure

Molecular Weight

335.465 g/mol

Physical State

Solid

Melting Point

Not Available

Water Solubility

Not Available

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP3A4; CYP2D6

Primary Drug Target
Name5-HT-1D Receptor
Gene NameHTR1D
Synonyms5-hydroxytryptamine 1D receptor; 5-HT-1D; Serotonin receptor 1D; 5- HT-1D-alpha
Specific FunctionThis is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity

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