Chemisty and Biological Activity
Chemical Formula
C5H4N4O
Chemical Name
3,5,7,8-tetrazabicyclo[4.3.0]nona-3,5,9-trien-2-one
Chemical Structure
Molecular Weight
136.112 g/mol
Physical State
Solid
Melting Point
350 oC
Water Solubility
569 mg/L
Isoelectric Point
Not Available
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
| Name | Xanthine oxidase | | Gene Name | XDH | | Synonyms | Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase; EC 1.17.1.4; XD; Xanthine oxidase; EC 1.17.3.2; XO; Xanthine oxidoreductase] | | General Function | Nucleotide transport and metabolism | | Specific Function | This enzyme can be converted from the dehydrogenase form (D) to the oxidase form (O) irreversibly by proteolysis or reversibly through the oxidation of sulfhydryl groups | | Pathway | map00230 Purine metabolism | | Reaction | xanthine + H2O + O2 = urate + H2O2 |
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