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Active ingredient: Alglucerase - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C2532H3854N672O711S16

Chemical Name

Human Beta-glucocerbrosidase

Chemical Structure

ARPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYESTRSGRRME LSMGPIQANHTGTGLLLTLQPEQKFQKVKGFGGAMTDAAALNILALSPPA QNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLP EEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQ PGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLG FTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPE AAKYVHGIAVHWYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQ SVRLGSWDRGMQYSHSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDS PIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDAVALM HPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ

Molecular Weight

55597.4

Physical State

Liquid

Melting Point

Not Available

Water Solubility

Not Available

Isoelectric Point

7.41

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameD-glucosyl-N-acylsphingosine
Pathwaymap00600 Glycosphingolipid metabolism
ReactionD-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine

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