Chemisty and Biological Activity
Chemical Formula
C4H13NO7P2
Chemical Name
(4-amino-1-hydroxy-1-phosphono-butyl)phosphonic acid
Chemical Structure
Molecular Weight
249.096 g/mol
Physical State
Solid
Melting Point
233 - 235 oC
Water Solubility
1mg/L
Isoelectric Point
2.72
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
| Name | Farnesyl pyrophosphate synthetase | | Gene Name | FDPS | | Synonyms | FPP synthetase; FPS; Farnesyl diphosphate synthetase[Includes: Dimethylallyltranstransferase, EC 2.5.1.1, Geranyltranstransferase, EC 2.5.1.10] | | General Function | Coenzyme transport and metabolism | | Specific Function | Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate | | Pathway | map00100 Biosynthesis of steroids
map00900 Terpenoid biosynthesis | | Reaction | geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate |
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