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Active ingredient: Albuterol - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C13H21NO3

Chemical Name

2-(hydroxymethyl)-4-(1-hydroxy-2-tert-butylamino-ethyl)-phenol

Chemical Structure

Molecular Weight

239.311 g/mol

Physical State

Solid

Melting Point

157-158oC

Water Solubility

3 mg/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameBeta-2 Adrenergic Receptor
Gene NameADRB2
SynonymsBeta-2 adrenergic receptor; Beta-2 adrenoceptor; Beta-2 adrenoreceptor
General FunctionReceptor activity and cell communication
Specific FunctionBeta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine

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