Active ingredient: Acrosoxacin - Brands, Medical Use, Clinical Data

Brands, Medical Use, Clinical Data

Drug Category

• Anti-Infective Agents

Dosage Forms

• Not Available

Brands / Synonyms

Eracine; Eradacil; Eradacin; ROS; Rosoxacin; Rosoxacin [Usan:Inn]; Rosoxacine [Inn-French]; Rosoxacino [Inn-Spanish]; Rosoxacinum [Inn-Latin]; Roxadyl; Winuron

Indications

For the treatment of Bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients

Pharmacology

Acrosoxacin is a nonfluorinated quinolone antibiotic. Its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase, which allows the untwisting required to replicate one DNA double helix into two. Acrosoxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.

Mechanism of Action

Acrosoxacin binds to and inhibits the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, repair, and recombination.

Absorption

Not Available

Toxicity

Not Available

Biotrnasformation / Drug Metabolism

Not Available

Contraindications

Not Available

Drug Interactions

Not Available