Chemisty and Biological Activity
Chemical Formula
C43H66O14
Chemical Name
[(2R,3R,4S,6S)-3-hydroxy-6-[(2R,4S,6S)-4-hydroxy-6-[(2R,3R,4S,6S)-4-hydroxy- 6-[[(5R,8R,9S,10S,13R,14S,17S)-14-hydroxy-10,13-dimethyl-17-(5-oxo-2H- furan-3-yl)-1,2,3,4,5,6,7,8,9,11,12,15,16,17- tetradecahydrocyclopenta[a]phenanthren-3-yl]oxy]-2-methyl-oxan-3-yl]oxy-2- methyl-oxan-3-yl]oxy-2-methyl-oxan-4-yl] acetate
Molecular Weight
806.976 g/mol
Physical State
Solid
Melting Point
Not Available
Water Solubility
0.0274 mg/L at 25 oC [MEYLAN,WM et al. (1996)]
Isoelectric Point
Not Available
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
| Name | Sodium/potassium-transporting ATPase alpha-1 chain | | Gene Name | ATP1A1 | | Synonyms | Sodium/potassium-transporting ATPase alpha-1 chain precursor; EC 3.6.3.9; Sodium pump 1; Na+/K+ ATPase 1 | | General Function | Inorganic ion transport and metabolism | | Specific Function | This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. | | Reaction | ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in) |
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