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Active ingredient: Acetaminophen - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula


Chemical Name


Chemical Structure

Molecular Weight

151.163 g/mol

Physical State


Melting Point


Water Solubility

14 mg/mL (very slightly soluble in cold water; considerably more soluble in hot water)

Isoelectric Point


Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)


Primary Drug Target
NameProstaglandin G/H synthase 1 precursor
Gene NamePTGS1
SynonymsEC; Cyclooxygenase-1; COX-1; Prostaglandin-endoperoxide synthase 1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1
Specific FunctionMay play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells
Pathwaymap00590 Prostaglandin and leukotriene metabolism
Reactionarachidonate + AH2 + 2 O2 = prostaglandin H2 + A + H2O

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