Chemisty and Biological Activity
Chemical Formula
C8H9NO2
Chemical Name
N-(4-hydroxyphenyl)acetamide
Chemical Structure
Molecular Weight
151.163 g/mol
Physical State
Solid
Melting Point
169-170.5oC
Water Solubility
14 mg/mL (very slightly soluble in cold water; considerably more soluble in hot water)
Isoelectric Point
9.38
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
CYP1A2
Primary Drug Target
Name | Prostaglandin G/H synthase 1 precursor | Gene Name | PTGS1 | Synonyms | EC 1.14.99.1; Cyclooxygenase-1; COX-1; Prostaglandin-endoperoxide synthase 1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1 | Specific Function | May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells | Pathway | map00590 Prostaglandin and leukotriene metabolism | Reaction | arachidonate + AH2 + 2 O2 = prostaglandin H2 + A + H2O |
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