Active ingredient: Acamprosate - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C5H11NO4S

Chemical Name

3-acetylaminopropane-1-sulfonic acid

Chemical Structure

Molecular Weight

181.211 g/mol

Physical State

Solid

Melting Point

Not Available

Water Solubility

Not Available

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target

Name	Glutamate [NMDA] receptor
Gene Name	GRIN3A
Synonyms	Glutamate [NMDA receptor subunit 3A precursor; N-methyl-D-aspartate receptor subtype NR3A; NMDAR-L
Specific Function	NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. May play a role in the development of dendritic spines. May play a role in PPP2CB-NMDAR mediated signaling mechanism