[Evaluation of the effectiveness of prostacyclin in the treatment of thrombosis
of the central retinal vein using a double-blind method]. [Article in Polish]
Author(s): Zygulska-Mach H(1), Mirkiewicz-Sieradzka B, Kostka-Trabka E, Grodzińska LL,
Dembińska-Kieć AD, Romanowska B, Bieroń K, Kedzior A, Basista MM.
Affiliation(s): Author information:
(1)Kliniki Okulistycznej AM w Krakowie.
Publication date & source: 1992, Klin Oczna. , 94(1):13-5
The patients were divided by chance into 2 groups: the first one (15 persons) was
given a natrium salt of prostacyclin (Epoprostenol Wellcome or Chinoin) in a dose
of 5 mg/kg/min. intravenously by an infusion pump in 5 infusions; the control
group (15 persons) received instead of prostacyclin a placebo (0.1 M glycine
buffer of pH 10.5). Besides all the patients were given Doxium or Calcium
dobesilate, Rutinoscorbin, Vitamin C, and Polopyrin S (Soluble Aspirin).
Immediately after the completion of the treatment the authors did not find any
essential differences between the examined groups. In prolonged observations
however one demonstrated a significantly smaller frequency of the development of
neovascularization in the eyes of persons treated by prostacyclin in comparison
with the control group.
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