[Kidney-tonifying and dampness-expelling Chinese herbal medicine combined with
doxazosin for the treatment of chronic epididymitis]. [Article in Chinese]
Author(s): Zhou YC, Xia GS, Xue YY, Zhang XD, Zheng LW, Jin BF.
Affiliation(s): Research Institute of Andrology, Nanjing University of Traditional Chinese
Medicine, Nanjing, Jiangsu 210046, China. ycun00@yahoo.com.cn
Publication date & source: 2010, Zhonghua Nan Ke Xue. , 16(12):1143-6
OBJECTIVE: To study the clinical effects of kidney-tonifying and
dampness-expelling Chinese herbal medicine combined with doxazosin in the
treatment of chronic epididymitis.
METHODS: A total of 64 patients with chronic epididymitis were equally randomized
into a treatment and a control group, the former treated with kidney-tonifying
and dampness-expelling Chinese herbal decoction combined with doxazosin, and the
latter given doxazosin only, both for 4 weeks. The clinical symptoms were
measured by Chronic Epididymitis Symptom Index (CESI), Self-Rating Anxiety Scale
(SAS) and Self-Rating Depression Scale (SDS) before and after the treatment, and
the therapeutic effects were evaluated.
RESULTS: After 4 weeks of medication, the total mean scores on CESI, pain, and
quality of life (QOL) were significantly decreased in both the treatment and the
control groups (P < 0.05), even more significantly in the former than in the
latter (P < 0.05), and so were the scores on SAS and SDS (P < 0.05), but with no
significant differences between the two groups (P > 0.05).
CONCLUSION: Either doxazosin alone or kidney-tonifying and dampness-expelling
Chinese herbal decoction combined with doxazosin is obviously effective on
chronic epididymitis, but the combined medication produces an even better
efficacy.
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