[Small-dose vardenafil restores erectile function after penile surgery].
Author(s): Zhang GS, Zhou J, Chen Q, Da J, Dong GQ, Jiang YQ, Wang Z, Cai ZK
Affiliation(s): Department of Urology, The Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, China.
Publication date & source: 2011-04, Zhonghua Nan Ke Xue., 17(4):322-4.
Publication type: English Abstract; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
OBJECTIVE: To investigate the impact of penile surgery on the erectile function of the patient and to evaluate the role of small-dose vardenafil in restoring the impaired penile erection. METHODS: Sixty cases of penile cavernosum surgery were equally and randomly divided into a vardenafil and a control group, the former treated 5 - 7 days after surgery with 10 mg vardenafil every other day, while the latter given vitamin E at 100 mg once a day, both for 12 weeks. The penile erectile function of the patients was evaluated with the IIEF-5 questionnaire before surgery and at 3 and 6 months after vardenafil medication. RESULTS: The mean IIEF-5 scores of the vardenafil group were 18.83 +/- 2.98 and 20.13 +/- 2.98 at 3 and 6 months after vardenafil medication, significantly higher than 14.21 +/- 3.62 before surgery (P > 0.05), while that of the control group was significantly decreased at 3 months as compared with the preoperative score (13.38 +/- 2.82 versus 15.80 +/- 3.02, P < 0.05). The vardenafil group showed the highest IIEF-5 score after surgery (P < 0.05). CONCLUSION: Long-term administration of small-dose vardenafil after penile surgery helps to restore and maintain penile erectile function.