[Treatment of external RF hyperthermia combining with alpha 1-adrenergic receptor blocker for patients with prostatodynia and chronic non-bacterial prostatitis]

Author(s): Wang J, Li J, Lu R, Wang JM

Affiliation(s): Department of Urology, People's First Hospital of Yuxi, Yuxi, Yunnan 653100, China.

Publication date & source: 2002, Zhonghua Nan Ke Xue., 8(1):48-50.

Publication type: Clinical Trial; Randomized Controlled Trial

OBJECTIVES: To evaluate a new effective treatment for prostatodynia (PD) and chronic non-bacterial prostatitis (CNP). METHODS: One hundred and thirty-six patients suffered from PD or CNP were divided randomly into experiment group (n = 76), which were treated with external RF hyperthermia (ERFH) combining with alpha 1-adrenergic receptor blocker Terazosin for 12 weeks, and control group (n = 60), which were only treated with ERFH. Symptoms scores, urodynamic indexes and expressed prostate secretion were recorded pre- and post-treatments. RESULTS: MFR and AFR were significantly improved and symptoms scores significantly decreased in both groups (P < 0.05). The efficacy was better in experiment group than that in control group. The combination treatment also led to a significantly decrease in MUP and MUCP (P < 0.05). Additionally, the leucocytes in expressed prostate secretion were also reduced in experiment group (P < 0.05). CONCLUSIONS: Treatment of ERFH combining with alpha 1-adrenergic receptor blocker for patients with PD or CNP was effective and had little side-effect, while the future curative effect should be observed furtherly.