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Recurrent lentigo maligna melanoma: regression associated with local azelaic acid 20%.

Author(s): Vereecken P, Heenen M

Affiliation(s): Department of Dermatology, Erasme University Hospital, Brussels, Belgium.

Publication date & source: 2002-01, Int J Clin Pract., 56(1):68-9.

Publication type: Case Reports

Azelaic acid has been used to treat different hyperpigmentary disorders because of its antimelanocyte activity. The efficacy of azelaic acid in the treatment of lentigo maligna and melanoma has already been described and this local treatment is considered by some as an alternative agent when other forms of therapy are not realisable. Here we report a case of a patient with local recurrence of a stage IV lentigo maligna melanoma of the cheek which cleared after treatment with azelaic acid cream 20%.

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